Neonatal Intensive Care Unit

Over the past decades, evidence has grown that NICU music therapy has positive effects. It reduces stress, supports brain development and fosters emotional bonding. Research also shows potential benefits for neurological, cardiac, pulmonary and gastrointestinal conditions.

With this project we aim to better understand how music therapy affects the health and development of neonates. Specifically, we investigate:

• the effects of music therapy on neurological and cardiological development
• potential influence on epigenetic changes
• how music can contribute to the development of an Active Noise Cancelling Incubator, designed to reduce disturbing sounds in neonatal care

We conduct a randomised controlled trial, comparing the effects of music therapy with standard care. We study both the infants’ physiological and neurological responses and the experiences of their parents. The research combines knowledge from music therapy, medical science and technology.

Earlier studies show that extremely and very preterm infants can respond to music therapy in two distinct ways. Some infants show reduced oxygen consumption and a lower heart rate, which may indicate a calming effect. Others show increased oxygen consumption and a higher heart rate, which may reflect a hyperalert state. These patterns suggest that music therapy activates the autonomic nervous system, which regulates heart rate and cerebral oxygenation. The clinical significance of these two different responses, and what they mean for early neurological development, is not yet fully understood. Further research is needed, and this project aims to explore exactly that.

This project brings together researchers, music therapists, medical professionals and technology partners. Together we develop new knowledge that will benefit neonatal care not only in the Netherlands but also internationally, giving vulnerable newborns a healthier start in life.